Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
![Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: Rat splenocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
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Abbre | CD47 |
Swissprot | |
Host | Mouse |
Reactivity | Human;Mouse;Rat |
Clonality | Monoclonal |
Applications | |
Research Areas | Immunology;Innate Immunity |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Rat splenocytes were stained with 0.2 μg Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.