Purified Anti-Mouse CD172a Antibody[P84]
![Purified Anti-Mouse CD172a Antibody[P84]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG1, κ
- 宿主： Rat
| Alternate Names | Myd, SHPS, Ptpns, Bit, Myd1, Ptpns1, Shps1, Sirp, Sirpa, SIRP&, beta-1-1, SIRP&, alpha, SIRP&, beta, AI835480, CD172a, P84, SHP-1, SHPS-1 |
| Clone No | |
| Isotype | Rat IgG1, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse bone marrow |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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| Background |
Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization. Receptor for THBS1. Interaction with THBS1 stimulates phosphorylation of SIRPA. In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production.
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| Immunogen | Recombinant Mouse CD172a protein |
| Abbre | CD172a |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Order now, ship in 3 days |
C57/BL6 Mouse bone marrow were stained with 0.2 μg Purified Anti-Mouse CD172a Antibody[P84] (Right) and 0.2 μg Rat IgG1, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
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