Purified Anti-Mouse CD86 Antibody[GL-1]
![Purified Anti-Mouse CD86 Antibody[GL-1]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
|
| Abbre | CD86 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Applications | |
| Research Areas | Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
C57/BL6 Mouse splenocytes were stained with 0.2 μg Purified Anti-Mouse CD86 Antibody[GL-1] (Right) and 0.2 μg Rat IgG2a, κ Isotype Control (Left), followed by PE-conjugated Goat Anti-Rat IgG Secondary Antibody.
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