Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator ( PLAT ) and urokinase-type plasminogen activator ( PLAU ) . As PLAT inhibitor , it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor , it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration , independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells , and regulates odontoblast differentiation and dentin formation during odontogenesis.

Endothelial Plasminogen Activator Inhibitor;PAI;PAI-1;PLANH1;SERPINE1

Rat

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月