Recombinant Human AGT protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P01019
| 别称 |
ANGT;ANHU;ANRT;AT-2;Aangiotensinogen;Alpha 1 antiproteinase antitrypsin;Ang;Angiotensin I;Angiotensin-3;PAT;SERPINA8;Serpin A8
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Met1-Glu476
|
| 蛋白编码 |
P01019
|
| 种属 |
Human
|
| 计算分子量 |
52.3 kDa
|
| 表观分子量 |
45-60 kDa
|
| 标签 |
C-His
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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实验操作视频
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