Recombinant Human APOA4 Protein(Sumo Tag)
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- 表达系统： E.coli
- 蛋白编码： P06727
| 别称 |
Apolipoprotein A;APOA4;Apo AIV;APOA 4;ApoA IV;ApoAIV;ApoA-IV;Apo-AIV;Apolipoprotein A IV;Apolipoprotein A4;Apolipoprotein A-IV;MGC142154;MGC142156;APOA4;Apolipoprotein A-IV;ApoA-IV;ApoAIV;apoA4;
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| 表达系统 |
E.coli
|
| 序列 |
Ser23-Ser396
|
| 蛋白编码 |
P06727
|
| 种属 |
Human
|
| 计算分子量 |
54 kDa
|
| 表观分子量 |
60 kDa
|
| 标签 |
N-Sumo
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drμgs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet.
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实验操作视频
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