Recombinant Human ATXN2 protein (GST Tag)
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- 表达系统： E.coli
- 蛋白编码： Q99700
| 别称 |
ATX2;ATXN2;Ataxin-2;SCA2;Spinocerebellar ataxia type 2 protein;TNRC13;Trinucleotide repeat-containing gene 13 protein
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| 表达系统 |
E.coli
|
| 序列 |
Leu460-Ser600
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| 蛋白编码 |
Q99700
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| 种属 |
Human
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| 计算分子量 |
40.4 kDa
|
| 表观分子量 |
42 kDa
|
| 标签 |
N-GST
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
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实验操作视频
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