Recombinant Human B-cell Receptor CD22/Siglec-2/CD22 (C-6His) Biotinylated-Elabscience伊莱瑞特【官网】

Recombinant Human B-cell Receptor CD22/Siglec-2/CD22 (C-6His) Biotinylated

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货号：PKSH033956
说明书

说明书

Recombinant Human B-cell Receptor CD22/Siglec-2/CD22 (C-6His) Biotinylated

Price: ¥7560.00 ¥2786.00

Size:

100 μg 20 μg

表达系统： HEK293 Cells
蛋白编码： P20273
应用性： BLI

别称	B-cell receptor CD22;B-lymphocyte cell adhesion molecule;BL-CAM;CD22;CD22 antigenMGC130020;CD22 molecule;SIGLEC2FLJ22814;Siglec-2;T-cell surface antigen Leu-14;sialic acid binding Ig-like lectin 2
表达系统	HEK293 Cells
序列	Asp20-Arg687
蛋白编码	P20273
种属	Human
计算分子量	78.0 kDa
表观分子量	110-130 kDa
标签	C-His-Avi
生物活性	Loaded Biotinylated Human Siglec-2-His-Avi on HIS1K Biosensor, can bind Anti-Human Siglec-2 mAb-Fc with an affinity constant of 0.16 nM as determined in BLI assay.
纯度	> 95 % as determined by reducing SDS-PAGE.
内毒素	< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件	This product is provided as lyophilized powder which is shipped with ice packs.
制剂	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
复溶方法	Please refer to the printed manual for detailed information.
背景	Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or B-lymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec-2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec-2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.

> 95 % as determined by reducing SDS-PAGE.

Loaded Biotinylated Human Siglec-2-His-Avi on HIS1K Biosensor, can bind Anti-Human Siglec-2 mAb-Fc with an affinity constant of 0.16 nM as determined in BLI assay.