Recombinant Human BAX Protein(Trx Tag)
Price:
- 表达系统： E.coli
- 蛋白编码： Q07812
| 别称 |
BCL2L4bcl2-L;Bcl-2-like protein;BCL2L;Bcl2-L;BAX;BCL2L4;apoptosis regulator BAX;Bcl2-L-4;BCL2L4bcl2-L-4;BCL2-associated X protein;Bcl-2-like protein 4;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bax-protein;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl-2-like protein 4 (Bcl2-L-4);membrane isoform alpha
|
| 表达系统 |
E.coli
|
| 序列 |
Met1-Trp158
|
| 蛋白编码 |
Q07812
|
| 种属 |
Human
|
| 计算分子量 |
37.4 kDa
|
| 表观分子量 |
35 kDa
|
| 标签 |
N-Trx
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
|
| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
|
| 背景 |
BCL2 associated X (BAX) is traditionally thoμght to be regulated by anti-apoptotic BCL-2 family members. BCL-2-associated X protein (BAX) is a critical apoptotic regulator that can be transformed from a cytosolic monomer into a lethal mitochondrial oligomer, The pro-apoptotic BCL-2 protein BAX commits human cells to apoptosis by permeabilizing the outer mitochondrial membrane. BAX activation has been sμggested to require the separation of helix alpha5 from alpha6 - the 'latch' from the 'core' domain - among other conformational changes. BCL-2-associated X (BAX) protein acts as a gatekeeper in regulating mitochondria-dependent apoptosis. Under cellular stress, BAX becomes activated and transforms into a lethal oligomer that causes mitochondrial outer membrane permeabilization (MOMP).
|
实验操作视频
新品推荐
Recombinant Mouse CXCL1 Protein(GST Tag)
Recombinant Human BCL2 Protein(GST Tag)
Recombinant Mouse Agrp Protein(GST Tag)
Recombinant Human S100A9 Protein(Trx Tag)
Recombinant Mouse Ceacam1 Protein(His Tag)
Recombinant Mouse Fetuin-A Protein(His Tag)
Recombinant Mouse CD3E Protein(Trx Tag)
Recombinant Human CD44 Protein(Trx Tag)
联系我们
