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Recombinant Human CA9 Protein(His Tag)

Recombinant Human CA9 Protein(His Tag)
  • Recombinant Human CA9 Protein(His Tag)
  • Recombinant Human CA9 Protein(His Tag)

Price: ¥3600.00 ¥1200.00

Size:
100 μg 20 μg
  • 表达系统: Mammalian
  • 蛋白编码: Q16790
别称
CA-IX;CA9;CAH9;CAIX;Carbonate dehydratase IX;Carbonic anhydrase 9;Carbonic anhydrase IX;Carbonic dehydratase;G250;Membrane antigen MN;MN;P54/58N;pMW1;RCC associated protein G250;RCC-associated antigen G250;Renal cell carcinoma-associated antigen G250
表达系统
Mammalian
序列
Gln38-Asp414
蛋白编码
Q16790
种属
Human
计算分子量
41.3 kDa
表观分子量
45-50 kDa
标签
C-His
生物活性
Not validated for activity
纯度
> 90% as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU/mg of the protein as determined by the LAL method
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
复溶方法
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
背景
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
SDS-PAGE analysis of Human CA9 proteins, 2 μg/lane of Recombinant Human CA9 proteins was resolved with an SDS-PAGE under reducing conditions, showing bands at 41.3KD


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