Recombinant Human CCL1/I-309 Protein
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- 表达系统： E.coli
- 蛋白编码： P22362
| 别称 |
CCL1;C-C Motif Chemokine 1;SCYA1;Small-Inducible Cytokine A1;T Lymphocyte-Secreted Protein I-309
|
| 表达系统 |
E.coli
|
| 序列 |
Lys24-Lys96
|
| 蛋白编码 |
P22362
|
| 种属 |
Human
|
| 计算分子量 |
8.6 kDa
|
| 表观分子量 |
10 kDa
|
| 标签 |
None
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a
central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a
homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence
identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.
CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface
chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell
fusion and virus infection.
|
实验操作视频
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