Recombinant Human CCL5/RANTES Protein
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- 表达系统： E.coli
- 蛋白编码： P13501
| 别称 |
C-C Motif Chemokine 5;CCL5;D17S136E;EoCP;Eosinophil Chemotactic Cytokine;SCYA5;SIS-Delta;Small-Inducible Cytokine A5;T Cell-Specific Protein P228;T-Cell-Specific Protein RANTES;TCP228
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| 表达系统 |
E.coli
|
| 序列 |
Ser24-Ser91
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| 蛋白编码 |
P13501
|
| 种属 |
Human
|
| 计算分子量 |
7.8 kDa
|
| 表观分子量 |
9-12 kDa
|
| 标签 |
None
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 6% Trehalose, 4% Mannitol, 0.05% Tween 80, pH4.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
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实验操作视频
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