Recombinant Human CD16b/FCGR3B Protein (Fc & His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： O75015
| 别称 |
CD16b and FCGR3B;FCG3;FCGR3;FCRIII;FCRIIIb;Fc-gamma RIII-beta;FcR-10;IgG Fc receptor III-1;Low affinity immunoglobulin gamma Fc region receptor III-B
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Gly17-Gln208
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| 蛋白编码 |
O75015
|
| 种属 |
Human
|
| 计算分子量 |
48.8 kDa
|
| 表观分子量 |
70 kDa
|
| 标签 |
C-Fc-His
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Low affinity immunoglobulin gamma Fc region receptor III-B; also known as Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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实验操作视频
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