Recombinant Human CD59 (C-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： P13987
| 别称 |
16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD59;CD59 antigen;CD59 glycoprotein;EL32;FLJ38134;FLJ92039;G344;HRF-20;HRF20;MAC-IP;MACIF;MIC11;MIC11MSK21;MIN1;MIN2;MIN3;MIRL;p18-20
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Leu26-Asn102
|
| 蛋白编码 |
P13987
|
| 种属 |
Human
|
| 计算分子量 |
9.8 kDa
|
| 表观分子量 |
15-20 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
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实验操作视频
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