Recombinant Human CHI3L1 protein(N-His)
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- 表达系统： E.coli
- 蛋白编码： P36222
| 别称 |
ASRT7;CGP-39;GP-39;GP39;HC-gp39;HCGP-3P;YK-40;YKL-40;YKL40;YYL-40;hCGP-39
|
| 表达系统 |
E.coli
|
| 序列 |
Tyr 22-Thr 383
|
| 蛋白编码 |
P36222
|
| 种属 |
Human
|
| 计算分子量 |
41.4 kDa
|
| 表观分子量 |
40 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 98 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Chitinase-3-like protein 1 (CHI3L1) also known as YKL-40, is a .secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheumatoid, arthritis,osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patients with osteoarthritis.CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
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实验操作视频
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