Recombinant Human CT1 Protein(Trx Tag)
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- 表达系统： E.coli
- 蛋白编码： Q16619-1
| 别称 |
Cardiophin 1;Cardiophin1;Cardiotrophin I;Cardiotrophin-1;Cardiotrophin1;CardiotrophinI;CT 1;CT-1;CT1;CTF 1;Ctf1;CTF1_HUMAN
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| 表达系统 |
E.coli
|
| 序列 |
Ser2-Ala201
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| 蛋白编码 |
Q16619-1
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| 种属 |
Human
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| 计算分子量 |
41.8 kDa
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| 表观分子量 |
39 kDa
|
| 标签 |
N-Trx
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
CTF1 is the first HOX11 protein partner identified that plays an important role in hematopoietic precursor cell immortalization. CTF1 was found to protect a gene from silencing when its DNA-binding sites were interposed between the gene and the telomeric extremity, while it did not affect a gene adjacent to the telomere. Protein fusions containing the CTF1 histone-binding domain displayed similar activities, while mutants impaired in their ability to interact with an the histone did not. Cardiotrophin-1 (CTF1) has been reported to act as a trophic factor for a few neurons, such as sensory, cholinergic, dopaminergic, motor and cortical neurons. Studies have indicated that CTF1 delays degenerative disease progression in motor neuron disease.
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实验操作视频
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