Recombinant Human CXCL1 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P09341
| 别称 |
C-X-C Motif Chemokine 1;CXCL1;GRO;GRO-Alpha(1-73);GRO1;GROA;Growth-Regulated Alpha Protein;MGSA;Melanoma Growth Stimulatory Activity;NAP-3;Neutrophil-Activating Protein 3;SCYB1
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| 表达系统 |
HEK293 Cells
|
| 序列 |
Ala35-Asn107
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| 蛋白编码 |
P09341
|
| 种属 |
Human
|
| 计算分子量 |
8.9 kDa
|
| 表观分子量 |
10-14 kDa
|
| 标签 |
C-His
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.01 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.
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实验操作视频
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