Recombinant Human CXCL3/CINC-2α/β Protein(Trx Tag)
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- 表达系统： E.coli
- 蛋白编码： P19876
| 别称 |
GRO;CXCL;SCYB;C-X-C Motif Chemokine;CINC-2b;C-X-C Motif Chemokine 3;GRO-Gamma;GRO-Gamma (1-73);GRO-Gamma (5-73);Growth-Regulated Protein Gamma;Macrophage Inflammatory Protein 2-Beta;MIP2B;MIP-2b;MIP2-Beta;CXCL3;GRO3;GROG;SCYB3
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| 表达系统 |
E.coli
|
| 序列 |
Cys35-Phe107
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| 蛋白编码 |
P19876
|
| 种属 |
Human
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| 计算分子量 |
27.9 kDa
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| 表观分子量 |
30 kDa
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| 标签 |
N-Trx
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
CXCL3/CINC-2α/β is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3/CINC-2α/β autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3/CINC-2α/β is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner throμgh induction of c/ebpb and c/ebpd. CXCL3/CINC-2α/β and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.
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实验操作视频
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