Recombinant Human CXCL5 Protein
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- 表达系统： E.coli
- 蛋白编码： P42830
- 应用性： Cell culture
| 别称 |
C-X-C Motif Chemokine 5;CXCL5;ENA-78 (1-78);ENA-78 (8-78);ENA-78 (9-78);ENA78;Epithelial-Derived Neutrophil-Activating Protein 78;Neutrophil-Activating Peptide ENA-78;SCYB5;Small-Inducible Cytokine B5
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| 表达系统 |
E.coli
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| 序列 |
Arg 45-Asn114
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| 蛋白编码 |
P42830
|
| 种属 |
Human
|
| 计算分子量 |
8.5 kDa
|
| 表观分子量 |
12 kDa
|
| 标签 |
N-His
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| 生物活性 |
Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2.The ED50 for this effect is <10 ng/mL.
|
| 纯度 |
> 98 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78). In vitro, ENA-78(8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers.
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实验操作视频
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