Recombinant Human CXCL7/NAP-2 Protein(Trx Tag)
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- 表达系统： E.coli
- 蛋白编码： P02775
| 别称 |
B-TG;CTAP;CXCL;SCYB;C-X-C Motif Chemokine;MDGFSmall-Inducible Cytokine B;LA-PF;NAP;PPBP;B-TG1;Beta-TG;CTAP-III;CTAP3;CTAPIII;CXCL7;LA-PF4;LDGF;MDGF;NAP-2;PBP;SCYB7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;C-X-C Motif Chemokine 7;Leukocyte-Derived Growth Factor;Macrophage-Derived Growth Factor;MDGFSmall-Inducible Cytokine B7;NAP2;Platelet Basic Protein;βTG;B TG1;Beta TG;Beta thromboglobulin;beta-1;Chemokine (C X C motif) ligand 7;Connective tissue activating peptide III;CTAP 3;CTAP III;CTAP-III(1-81);CXC chemokine ligand 7;CXCL 7;LA PF 4;Leukocyte derived growth factor;Low-affinity platelet factor IV;NAP 2;NAP-2(1-63);NAP-2(1-66);NAP-2(73);NAP-2(74);Neutrophil activating peptide 2;Neutrophil-activating peptide 2(1-63);Pro platelet basic protein;Pro platelet basic protein (chemokine (C-X-C motif) ligand 7);Pro-Platelet basic protein;Small inducible cytokine subfamily B member 7;Small-inducible cytokine B7;Thrombocidin 1;Thrombocidin 2;Thromboglobulin;βTG;PBP;CXCL7;NAP2;β-thromboglobulin
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| 表达系统 |
E.coli
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| 序列 |
Ala59-Asp128
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| 蛋白编码 |
P02775
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| 种属 |
Human
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| 计算分子量 |
27.6 kDa
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| 表观分子量 |
30 kDa
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| 标签 |
N-Trx
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.
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实验操作视频
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