Recombinant Human Galectin-3 Protein(His Tag)
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- 表达系统： E.coli
- 蛋白编码： P17931
| 别称 |
MAC;Galactose-specific lectin;Galactoside-Binding Soluble;Galectin;Lectin L;GAL;CBP;LGALS3;CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2;Galactoside-Binding Soluble 3;Lectin;Galectin-3;Gal-3;L-31;35 kDa lectin;CBP 35;Galactose-specific lectin 3;IgE-binding protein;Laminin-binding protein;Lectin L-29;Mac-2 antigen;Carbohydrate binding protein 35;Carbohydrate-binding protein 35;galactose binding;galactoside binding soluble 3;Galactoside-binding protein;galectin 3;Galectin 3 internal gene;Galectin3;GBP;IgE binding protein;included;L 31;L 34;L-34 galactoside-binding lectin;Lectin;Galactoside-Binding Soluble 3;LEG3;MAC 2 antigen;Mac-2;Macrophage galactose-specific lectin;MGC105387;P35;soluble 3
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| 表达系统 |
E.coli
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| 序列 |
2Ala-250Iie
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| 蛋白编码 |
P17931
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| 种属 |
Human
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| 计算分子量 |
27.4 kDa
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| 表观分子量 |
32 kDa
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| 标签 |
N-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Galectin-3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. Galectin-3 has an important role in tumor progression throμgh inhibition of apoptosis. Galectin-3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of Galectin-3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with Galectin-3 include Follicular Adenoma and Papillary Carcinoma.
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实验操作视频
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