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Recombinant Human ICAM-1/CD54 Protein (Fc Tag)

Recombinant Human ICAM-1/CD54 Protein (Fc Tag)
  • Recombinant Human ICAM-1/CD54 Protein (Fc Tag)
  • Recombinant Human ICAM-1/CD54 Protein (Fc Tag)

Price: ¥2576.00 ¥966.00

Size:
50 μg 10 μg
  • 表达系统: HEK293 Cells
  • 蛋白编码: P05362
别称
CD54;ICAM-1;ICAM1;Intercellular Adhesion Molecule 1;Major Group Rhinovirus Receptor
表达系统
HEK293 Cells
序列
Asn26-Glu480
蛋白编码
P05362
种属
Human
计算分子量
76.8 kDa
表观分子量
90-125 kDa
标签
C-Fc
生物活性
Not validated for activity
纯度
> 90 % as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
复溶方法
Please refer to the printed manual for detailed information.
背景
Inter-Cellular Adhesion Molecule 1 (ICAM1) is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration. The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands. Notably, ICAM-1 binds to macrophage adhesion ligand-1 (Mac-1; ITGB2 / ITGAM), leukocyte function associated antigen-1 (LFA-1/integrin), and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.
> 90 % as determined by reducing SDS-PAGE.


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