Recombinant Human IFNAR1 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： P17181-1
| 别称 |
CRF2-1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;IFN-R-1 IFN-alpha/beta receptor 1;IFNAR;Interferon alpha/beta receptor 1;Type I interferon receptor 1
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| 表达系统 |
E.coli
|
| 序列 |
Lys28-Leu200
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| 蛋白编码 |
P17181-1
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| 种属 |
Human
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| 计算分子量 |
20.0 kDa
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| 表观分子量 |
24 kDa
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| 标签 |
N-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 . Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha-and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.
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实验操作视频
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