Recombinant Human IFNGR1 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P15260
| 别称 |
CD119;IFNGR;IFNGR1;IMD27A;IMD27B;Interferon gamma receptor 1
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Glu18-Ser245
|
| 蛋白编码 |
P15260
|
| 种属 |
Human
|
| 计算分子量 |
26.8 kDa
|
| 表观分子量 |
40-50 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
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