Recombinant Human IL17RA Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q96F46
- 应用性： ELISA
| 别称 |
IMD;MGC;CTLA;CANDF;CDw;IL17RA;CANDF5;CD217;CDw217;IL-17RA;IL17R;IMD51;hIL-17R;CD127;CD217 antigen;CDW127;CTLA8;HIL 17R;hIL17R;I17RA;IL 17 receptor;IL 17 receptor A;IL 17RA;IL17;IL-17 R alpha;IL-17 receptor A;IL17A receptor;IL-17R;IL17R-A;IL17-RA;IL-17R-alpha;IL7RA;ILRA;Interleukin 17 receptor A;Interleukin-17 receptor A;MGC10262; CDw217;Interleukin-17 receptor A
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| 表达系统 |
HEK293 Cells
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| 序列 |
Leu33-Trp320
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| 蛋白编码 |
Q96F46
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| 种属 |
Human
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| 计算分子量 |
60.6 kDa
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| 表观分子量 |
90-120 kDa
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| 标签 |
C-Fc
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| 生物活性 |
Immobilized Human IL-17RA-Fc at 2μg/ml (100 μl/well)can bind Anti-Human IL-17RA mAb.The ED50 of Anti-Human IL-17RA mAb is 13.50 ng/ml.
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure.
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实验操作视频
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