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Recombinant Human IL-10 Protein(Trx Tag)

Recombinant Human IL-10 Protein(Trx Tag)
  • Recombinant Human IL-10 Protein(Trx Tag)
  • Recombinant Human IL-10 Protein(Trx Tag)

Price: ¥3600.00 ¥1200.00

Size:
100 μg 20 μg
  • 表达系统: E.coli
  • 蛋白编码: P22301
别称
CSIF;Cytokine synthesis inhibitory factor;GVHDS;IL 10;IL-10;IL10;IL10;IL10A;Interleukin 10;Interleukin-10;MGC126450;MGC126451;T-cell growth inhibitory factor;TGIF
表达系统
E.coli
序列
Ser19-Asn178
蛋白编码
P22301
种属
Human
计算分子量
27.5 kDa
表观分子量
35 kDa
标签
N-Trx
生物活性
Not validated for activity
纯度
> 90% as determined by reducing SDS-PAGE.
内毒素
< 10 EU/mg of the protein as determined by the LAL method
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
复溶方法
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
背景
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
SDS-PAGE analysis of Human IL-10 proteins, 2 μg/lane of Recombinant Human IL-10 proteins was resolved with an SDS-PAGE under reducing conditions, showing bands at 35 KD


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