Recombinant Human IL-16 (129 a.a.) protein(N-His)
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- 表达系统： E.coli
- 蛋白编码： Q14005
| 别称 |
NIL;Interleukin;IL16;LCF;NIL16;PRIL16;prIL-16;IL-16;Interleukin-16;LCF (Lymphocyte Chemoattractant Factor);Lymphocyte chemoattractant factor;Pro-Interleukin-16
|
| 表达系统 |
E.coli
|
| 序列 |
Met 1203-Ser 1332
|
| 蛋白编码 |
Q14005
|
| 种属 |
Human
|
| 计算分子量 |
14.1 kDa
|
| 表观分子量 |
18 kDa
|
| 标签 |
C-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from sterile PBS,pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
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实验操作视频
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