Recombinant Human IL-26 protein(His Tag)
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- 表达系统： E.coli
- 蛋白编码： Q9NPH9
- 应用性： Cell culture
| 别称 |
Protein AK;AK155;IL-26;IL26;IL 26;Interleukin 26;Interleukin-26;Protein AK155
|
| 表达系统 |
E.coli
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| 序列 |
Lys 22-Gln 171
|
| 蛋白编码 |
Q9NPH9
|
| 种属 |
Human
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| 计算分子量 |
18.5 kDa
|
| 表观分子量 |
18 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Measure by its ability to induce IL-10 secretion in COLO205 cells. The ED50 for this effect is <150 ng/mL.
|
| 纯度 |
> 98 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from sterile PBS,pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
May play a role in local mechanisms of mucosal immunity and seems to have a pro-inflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
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实验操作视频
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