Recombinant Human IL-2RB/CD122 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P14784
- 应用性： BLI
| 别称 |
P70;IL2RB;CD122;IL15RB;P70-75;IL-2Rβ;p75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75);IL-2RβCD122 antigen;High affinity IL 2 receptor beta subunit;High affinity IL 2 receptor subunit beta;IL2 receptor;Interleukin 2 receptor beta;interleukin 2 receptor subunit beta;P70 75;P7075
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| 表达系统 |
HEK293 Cells
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| 序列 |
Ala27-Asp239
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| 蛋白编码 |
P14784
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| 种属 |
Human
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| 计算分子量 |
51.7 kDa
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| 表观分子量 |
60-80 kDa
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| 标签 |
C-Fc
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| 生物活性 |
Loaded Biotinylated Human IL-2-His-Avi on SA Biosensor, can bind Human IL-2RB-Fc with an affinity constant of 12.62nM as determined in BLI assay.
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Human IL-2RB; also known asinterleukin-2 receptor subunit beta;is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein;and has a 26 residue signal peptide; a 214 residue extracellular region; a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules; such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
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实验操作视频
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