Recombinant Human Interleukin-17F/IL-17F Protein
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- 表达系统： E.coli
- 蛋白编码： Q96PD4
- 应用性： Cell culture
| 别称 |
Cytokine ML;Interleukin;CANDF;IL17F;CANDF6;IL-17F;ML-1;ML1;Cytokine ML-1;IL24;IL-24;Interleukin-17F;Interleukin-24
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| 表达系统 |
E.coli
|
| 序列 |
Arg31-Gln163
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| 蛋白编码 |
Q96PD4
|
| 种属 |
Human
|
| 计算分子量 |
15.8 kDa
|
| 表观分子量 |
18 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <20 ng/mL.
|
| 纯度 |
> 98 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from sterile 20 mM sodium acetate, pH 4.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today; IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family; IL-17A through IL-17F; are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
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实验操作视频
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