Recombinant Human LGALS7 Protein(Trx Tag)
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- 表达系统： E.coli
- 蛋白编码： P47929
| 别称 |
Gal-7;GAL7;Galectin 7B;Galectin-7;HKL-14;Human keratinocyte lectin 14;Keratinocyte lectin 14;Lectin galactoside binding soluble 7;Lectin;galactoside binding;soluble;7B;LEG7;LGALS7;LGALS7A;LGALS7B;P53 induced protein 1;p53-induced gene 1 protein;Pi7;PIG1;TP53I1
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| 表达系统 |
E.coli
|
| 序列 |
Ser2-Phe136
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| 蛋白编码 |
P47929
|
| 种属 |
Human
|
| 计算分子量 |
34.8 kDa
|
| 表观分子量 |
34.8 kDa
|
| 标签 |
N-Trx
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members of this family. Galectins share similarities in the CRD (the carbohydrate recognition domain). They are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or targeted to the nucleus. Galectins are implicated in modulating cell-cell and cell-matrix interactions. LGALS7 contains 1 galectin domain and is mainly expressed in stratified squamous epithelium. Galectin-7 could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. LGALS7 is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
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实验操作视频
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