Recombinant Human MCP-1 protein (GST Tag)

Price:
- 表达系统: E.coli
- 蛋白编码: P13500
别称 |
C-C motif chemokine 2;CCL2;HC11;MCAF;MCP-1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Monocyte secretory protein JE
|
表达系统 |
E.coli
|
序列 |
Gln24-Thr99
|
蛋白编码 |
P13500
|
种属 |
Human
|
计算分子量 |
33.3 kDa
|
表观分子量 |
35 kDa
|
标签 |
N-GST
|
生物活性 |
Not validated for activity
|
纯度 |
> 95% as determined by reducing SDS-PAGE.
|
内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
|
保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
|
复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
|
背景 |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
|
实验操作视频
新品推荐
Recombinant Mouse CXCL1 Protein(GST Tag)
Recombinant Human BCL2 Protein(GST Tag)
Recombinant Mouse Agrp Protein(GST Tag)
Recombinant Human S100A9 Protein(Trx Tag)
Recombinant Mouse Ceacam1 Protein(His Tag)
Recombinant Mouse Fetuin-A Protein(His Tag)
Recombinant Mouse CD3E Protein(Trx Tag)
Recombinant Human CD44 Protein(Trx Tag)