Recombinant Human NRP2 Protein(hIgG1 Fc Tag)
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- 表达系统： Mammalian
- 蛋白编码： O60462
| 别称 |
PRO;NPN;NRP;neuropilin;vascular endothelial growth factor-165 receptor;VEGF165R;NRP2;NP2;NPN2;PRO2714;VEGF165R2;neuropilin-2;vascular endothelial growth factor-165 receptor 2;MGC126574;Neuropilin 2;Neuropilin2;NP 2;NPN 2;NRP 2;Receptor for VEGF165 and semaphorins class3;Vascular endothelial cell growth factor 165 receptor 2;Vascular endothelial growth factor 165 receptor 2;VEGF1265R2
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| 表达系统 |
Mammalian
|
| 序列 |
Val20-Glu855
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| 蛋白编码 |
O60462
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| 种属 |
Human
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| 计算分子量 |
116.9 kDa
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| 表观分子量 |
120 kDa
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| 标签 |
C-hIgG1 Fc
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
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| 背景 |
Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are known to be important in angiogenesis, lymphangiogenesis, and axon guidance. The Neuropilin-family consists of two members, Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2). NRP2 is important for migration, antigen presentation, phagocytosis and cell-cell contact within the immune system. Additionally, posttranslational NRP2 modifications like polysialylation are crucial for the function of some immune cells.
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实验操作视频
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