Recombinant Human PD-L2/CD273 Protein (mFc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q9BQ51
| 别称 |
B7-DC;B7DC;Butyrophilin B7-DC;CD273;PD-1 Ligand 2;PD-L2;PDCD1 Ligand 2;PDCD1L2;PDCD1LG2;PDL2;Programmed Cell Death 1 Ligand 2;Programmed Death Ligand 2
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| 表达系统 |
HEK293 Cells
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| 序列 |
Leu20-Pro219
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| 蛋白编码 |
Q9BQ51
|
| 种属 |
Human
|
| 计算分子量 |
49.2 kDa
|
| 表观分子量 |
60-90 kDa
|
| 标签 |
C-mFc
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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实验操作视频
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