Recombinant Human RANTES protein (GST&His Tag)
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- 表达系统： E.coli
- 蛋白编码： P13501
| 别称 |
C-C Motif Chemokine 5;CCL5;D17S136E;EoCP;Eosinophil Chemotactic Cytokine;SCYA5;SIS-Delta;Small-Inducible Cytokine A5;T Cell-Specific Protein P228;T-Cell-Specific Protein RANTES;TCP228
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| 表达系统 |
E.coli
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| 序列 |
Pro25-Ser91
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| 蛋白编码 |
P13501
|
| 种属 |
Human
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| 计算分子量 |
32.3 kDa
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| 表观分子量 |
42 kDa
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| 标签 |
N-GST & C-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
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实验操作视频
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