Recombinant Human RCN2 (C-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q14257
| 别称 |
E6BP;ERC55;RCN2;Reticulocalbin-2
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Gly23-Leu317
|
| 蛋白编码 |
Q14257
|
| 种属 |
Human
|
| 计算分子量 |
35.6 kDa
|
| 表观分子量 |
50-55 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM DTT, pH 8.0.
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| 复溶方法 |
Not Applicable
|
| 背景 |
Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited.
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实验操作视频
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