Recombinant Human RGMA Protein (E.coli, His Tag)
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- 表达系统： E.coli
- 蛋白编码： AAI51133.1
| 别称 |
RGM;RGM domain family member A;Repulsive guidance molecule A
|
| 表达系统 |
E.coli
|
| 序列 |
Pro169-Gly422
|
| 蛋白编码 |
AAI51133.1
|
| 种属 |
Human
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| 计算分子量 |
29.8 kDa
|
| 表观分子量 |
30 kDa
|
| 标签 |
N-His
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 50% Glycerol, 1mM DTT, 0.05% Tween 80, pH 7.8.
|
| 复溶方法 |
Not Applicable
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| 背景 |
Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1; BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
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实验操作视频
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