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Recombinant Human S100A1 Protein(Trx Tag)

Recombinant Human S100A1 Protein(Trx Tag)
  • Recombinant Human S100A1 Protein(Trx Tag)
  • Recombinant Human S100A1 Protein(Trx Tag)

Price: ¥3600.00 ¥1200.00

Size:
100 μg 20 μg
  • 表达系统: E.coli
  • 蛋白编码: P23297
别称
Bpb;NEF;Protein S100-A1;S-100 protein alpha chain;S-100 protein subunit alpha;S100 alpha;S100 beta;S100 calcium binding protein A1;S100 calcium binding protein B;S100 calcium-binding protein A1;S100 protein alpha polypeptide;S100A;s100a1;S100B;S100beta;S10A1
表达系统
E.coli
序列
Met1-Ser94
蛋白编码
P23297
种属
Human
计算分子量
30.3 kDa
表观分子量
30 kDa
标签
N-Trx
生物活性
Not validated for activity
纯度
> 90% as determined by reducing SDS-PAGE.
内毒素
< 10 EU/mg of the protein as determined by the LAL method
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
复溶方法
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
背景
Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600). In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes (PubMed:23351007). These changes allow interactions with specific target proteins and modulate their activity (PubMed:22399290). Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase (PubMed:12804600). Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole.
SDS-PAGE analysis of Human S100A1 proteins, 2 μg/lane of Recombinant Human S100A1 proteins was resolved with SDS-PAGE under reducing conditions, showing bands at 30.3 KD


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