Recombinant Human TGFBR2 Protein (Fc Tag)
Price:
- 表达系统： HEK293 Cells
- 蛋白编码： P37173
- 应用性： Cell culture
| 别称 |
AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;TGF-beta receptor type-2;TGF-beta type II receptor;TGFBR2;TGFR-2;TGFbeta-RII;Transforming growth factor-beta receptor type II
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Thr 23-Asp159
|
| 蛋白编码 |
P37173
|
| 种属 |
Human
|
| 计算分子量 |
42.6 kDa
|
| 表观分子量 |
59 kDa
|
| 标签 |
C-Fc
|
| 生物活性 |
Measured by its ability to inhibit TGF-beta 1 activity on TF‑1 human erythroleukemic cells. The ED50 for this effect is 18.41 ng/ml in the presence of 100pg/ml of recombinant human TGF-beta 1.
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.
|
实验操作视频
新品推荐
Recombinant Mouse CXCL1 Protein(GST Tag)
Recombinant Human BCL2 Protein(GST Tag)
Recombinant Mouse Agrp Protein(GST Tag)
Recombinant Human S100A9 Protein(Trx Tag)
Recombinant Mouse Ceacam1 Protein(His Tag)
Recombinant Mouse Fetuin-A Protein(His Tag)
Recombinant Mouse CD3E Protein(Trx Tag)
Recombinant Human CD44 Protein(Trx Tag)
联系我们
