Recombinant Human TLR2 Protein(His Tag)
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- 表达系统： Mammalian
- 蛋白编码： O60603
| 别称 |
CD282;CD282 antigen;TIL 4;TIL4;TLR 2;TLR2;TLR2;Toll like receptor 2;Toll like receptor 2 precursor;Toll-like receptor 2;Toll/interleukin 1 receptor like 4;Toll/interleukin 1 receptor like protein 4;Toll/interleukin receptor like protein 4;Toll/interleukin-1 receptor-like protein 4
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| 表达系统 |
Mammalian
|
| 序列 |
Glu21-Leu590
|
| 蛋白编码 |
O60603
|
| 种属 |
Human
|
| 计算分子量 |
62.5 kDa
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| 表观分子量 |
70-80 kDa
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| 标签 |
C-His
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
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实验操作视频
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