Recombinant Human TNFSF4/OX40L protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P23510
| 别称 |
CD134L;CD252;GP34;Glycoprotein Gp34;OX-40;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;TNFSF4;TXGP1;Tumor necrosis factor ligand superfamily member 4
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| 表达系统 |
HEK293 Cells
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| 序列 |
Gln51-Leu183
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| 蛋白编码 |
P23510
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| 种属 |
Human
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| 计算分子量 |
14.5 kDa
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| 表观分子量 |
30 kDa
|
| 标签 |
C-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells,T cells,dendritic cells and endothelial cells. OX40L binds to OX40(CD134),a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional,it has been found association with systemic lupus erythematosus,no association with occurrence of atherosclerosis.
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实验操作视频
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