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Recombinant Mouse ABL1/c-Abl protein (His Tag)

Recombinant Mouse ABL1/c-Abl protein (His Tag)
  • Recombinant Mouse ABL1/c-Abl protein (His Tag)
  • Recombinant Mouse ABL1/c-Abl protein (His Tag)

Price: ¥3600.00 ¥1200.00

Size:
100 μg 20 μg
  • 表达系统: E.coli
  • 蛋白编码: P00520
别称
ABL 1;Abelson tyrosine protein kinase 1;JTK7;Proto-oncogene c-Abl;bcr/abl;p150;v abl
表达系统
E.coli
序列
Met1-Asn193
蛋白编码
P00520
种属
Mouse
计算分子量
21.1 kDa
表观分子量
25 kDa
标签
N-His
生物活性
Not validated for activity
纯度
> 95% as determined by reducing SDS-PAGE.
内毒素
< 10 EU/mg of the protein as determined by the LAL method
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
复溶方法
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
背景
Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
> 95 % as determined by reducing SDS-PAGE.


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