Apm;GBP;Acrp;ADIPQTL;ADIPQTL1;ADPN;GBP28;Acdc;Acrp30;Apm1;Adipoq;ACDC;AdipoQ;ADIPQTL1;ADPN;APM1;GBP28;30 kDa adipocyte complement related protein;30 kDa adipocyte complement-related protein;ADIPO;Adipocyte;Adipocyte C1q and collagen domain containing protein;Adipocyte complement related 30 kDa protein;Adipocyte complement related protein of 30 kDa;Adipocyte complement-related 30 kDa protein;adipocyte-specific secretory protein;Adiponectin;Adiponectin precursor;Adipose most abundant gene transcript 1;Adipose most abundant gene transcript 1 protein;Adipose specific collagen like factor;APM 1;apM-1;C1Q and collagen domain containing;C1q and collagen domain-containing protein;Gelatin binding protein;Gelatin binding protein 28;Gelatin-binding protein

E.coli

Glu18-Asn247

Q60994

Mouse

45.3 kDa

42 kDa

N-Trx

Not validated for activity

> 95% as determined by reducing SDS-PAGE.

< 10 EU/mg of the protein as determined by the LAL method

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

This product is provided as lyophilized powder which is shipped with ice packs.

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.