Recombinant Mouse CCL12 Protein(Trx Tag)
Price:
- 表达系统： E.coli
- 蛋白编码： Q62401
| 别称 |
Ccl;Mcp;Scya;CCL12/MCP;C-C motif chemokine;Small-inducible cytokine A;Monocyte chemoattractant protein;CCL12/MCP-5;CCL12;Mcp5;Scya12;C-C motif chemokine 12;MCP-1-related chemokine;Monocyte chemoattractant protein 5;Monocyte chemotactic protein 5 (MCP-5);Small-inducible cytokine A12
|
| 表达系统 |
E.coli
|
| 序列 |
Gly23-Gly104
|
| 蛋白编码 |
Q62401
|
| 种属 |
Mouse
|
| 计算分子量 |
28.9 kDa
|
| 表观分子量 |
32 kDa
|
| 标签 |
N-Trx
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
|
| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
|
| 背景 |
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 and MCP-5 are HIF-1 target genes and that HIF-1alpha is involved in transcriptional induction of these two chemokines in astrocytes by hypoxia.
|
实验操作视频
新品推荐
Recombinant Mouse CXCL1 Protein(GST Tag)
Recombinant Human BCL2 Protein(GST Tag)
Recombinant Mouse Agrp Protein(GST Tag)
Recombinant Human S100A9 Protein(Trx Tag)
Recombinant Mouse Ceacam1 Protein(His Tag)
Recombinant Mouse Fetuin-A Protein(His Tag)
Recombinant Mouse CD3E Protein(Trx Tag)
Recombinant Human CD44 Protein(Trx Tag)
联系我们
