Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P41272
| 别称 |
CD27 antigen;CD27L receptor;S152;T-cell activation antigen CD27;Tnfrsf7;Tp55;Tumor necrosis factor receptor superfamily member 7
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Pro24-Arg182
|
| 蛋白编码 |
P41272
|
| 种属 |
Mouse
|
| 计算分子量 |
45.8 kDa
|
| 表观分子量 |
50-70 kDa
|
| 标签 |
C-Fc-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
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实验操作视频
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