Recombinant Mouse CD38 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P56528
| 别称 |
ADPRC 1-rs1;ADPRC1;CD38;CD38 antigen;CD38 antigen (p45);CD38 molecule;Cd38;Cd38-rs1;Cyclic ADP-ribose Hydrolase;Cyclic ADP-ribose hydrolase 1;EC 3.2.2.5;I-19;NAD(+) nucleosidase;T10;cADPr hydrolase 1
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| 表达系统 |
HEK293 Cells
|
| 序列 |
Leu45-Thr304
|
| 蛋白编码 |
P56528
|
| 种属 |
Mouse
|
| 计算分子量 |
56.9 kDa
|
| 表观分子量 |
70-90 kDa
|
| 标签 |
C-Fc
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, PH7.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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实验操作视频
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