Recombinant Mouse CXCL1 Protein(GST Tag)
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- 表达系统： E.coli
- 蛋白编码： P12850
| 别称 |
CXCL;SCYB;Secretory protein N;Neutrophil-Activating Protein;GROα/CXCL;C-X-C Motif Chemokine 1;GRO-A;GRO-Alpha(1-73);Growth-Regulated Alpha Protein;GROα/CXCL1;Melanoma Growth Stimulatory Activity;NAP3;Neutrophil-Activating Protein 3;Platelet-derived growth factor-inducible protein KC;Secretory protein N51;CINC1;CINC-1;CXCL1;FSP;GRO1;GROa;KC;MGSA;MGSA-a;MGSA-alpha;NAP-3;SCYB1;GRO alpha;Growth Regulated Oncogene Alpha;Gro
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| 表达系统 |
E.coli
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| 序列 |
Ala25-Lys96
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| 蛋白编码 |
P12850
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| 种属 |
Mouse
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| 计算分子量 |
33.9 kDa
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| 表观分子量 |
40 kDa
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| 标签 |
N-GST
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 95% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
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| 背景 |
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the orthologs of the human GROs and rat CINCs. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.
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实验操作视频
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