Recombinant Mouse Galectin 9/LGALS9 Protein (GST Tag)
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- 表达系统： E.coli
- 蛋白编码： O08573-2
| 别称 |
Gal-9;Galectin-9;Lgals9
|
| 表达系统 |
E.coli
|
| 序列 |
Met1-Thr322
|
| 蛋白编码 |
O08573-2
|
| 种属 |
Mouse
|
| 计算分子量 |
62.8 kDa
|
| 表观分子量 |
58 kDa
|
| 标签 |
N-GST
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 85 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM β-Mercaptoethanol, 5% Trehalose, 400mM NaCl, pH6.5.
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| 复溶方法 |
Not Applicable
|
| 背景 |
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
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实验操作视频
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