Recombinant Mouse Il17F Protein(Sumo Tag)
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- 表达系统： E.coli
- 蛋白编码： Q7TNI7
| 别称 |
CANDF6;Cytokine ML 1;Cytokine ML-1;IL 17F;IL 24;IL-17F;Il17f;IL17F;Interleukin 17F;Interleukin 24;Interleukin-17F;ML 1;ML1;Mutant IL 17F;OTTHUMP00000016602
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| 表达系统 |
E.coli
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| 序列 |
Arg29-Ala161
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| 蛋白编码 |
Q7TNI7
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| 种属 |
Mouse
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| 计算分子量 |
27.5 kDa
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| 表观分子量 |
34 kDa
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| 标签 |
N-Sumo
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. Mouse and human IL-17F share 55% sequence identity.IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
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实验操作视频
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