Recombinant Mouse IL-11 protein(His Tag)

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- 表达系统: E.coli
- 蛋白编码: P47873
- 应用性: Cell culture
别称 |
Interleukin;IL-11;Interleukin-11;Zcyto1;Zcyto10;Il11;AGIF;interleukin 11
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表达系统 |
E.coli
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序列 |
Pro 22-Leu 199
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蛋白编码 |
P47873
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种属 |
Mouse
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计算分子量 |
20.0 kDa
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表观分子量 |
17-25 kDa
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标签 |
N-His
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生物活性 |
Measure by its ability to induce T11 cells proliferation.The ED50 for this effect is <0.5 ng/mL.The specific activity of recombinant mouse IL-11 is > 2 x 106 IU/mg.
|
纯度 |
> 98 % as determined by reducing SDS-PAGE.
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内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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制剂 |
Lyophilized from sterile PBS,pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.
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实验操作视频
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